Some applications I notice go to speakers that are still disabled. Try and seek where the audio is being sent to because odds are is could very well be in “headphone mode” which has disabled sound for me before.
I have the same problem, with a very similar Spec PC. No sound anywhere in the game, from main screen through to the whole of the game.
I’ve also noticed as soon as I try to fire a gun, the muzzle flash stays on screen like a firework out of the end of the barrel, do you have this problem as well?
Have you had any feedback from the Dev’s about a fix or a settings adjustment?